Jill Simmmons, MD

Physician, Professor of Pediatrics

Division of Pediatric Endocrinology and Diabetes

About Dr. Simmons

Dr. Jill Simmons is a Professor of Pediatrics in the Ian M. Burr Division of Pediatric Endocrinology and Diabetes at Vanderbilt University Medical Center. She graduated from the University of Tennessee College of Medicine, and she completed her pediatric residency and fellowship in Pediatric Endocrinology and Diabetes at the University of Colorado Children’s Hospital and Barbara Davis Center for Childhood Diabetes. She joined the faculty at Vanderbilt University Medical Center in 2006. She is the founder and director of the Vanderbilt Program for Pediatric Metabolic Bone Disease, the founder and chair of the Hazinski Society for Faculty Development, and the Director for Faculty Mentorship Programs at Vanderbilt University.

Dr. Simmons' clinical and research interests include pediatric metabolic bone diseases such as hypophosphatasia, osteogenesis imperfecta, osteoporosis, and rickets. She also is a local principal investigator in the Type 1 Diabetes Exchange, a multi-institutional collaboration to improve the lives and care of patients with type 1 diabetes.

Dr. Simmons' research has been presented at the Scientific Sessions of the American Diabetes Association, and the annual meetings of the Pediatric Academic Societies, the Endocrine Society, and the European Society for Pediatric Endocrinology. Her work has been published in the New England Journal of Medicine, Journal of Pediatrics, Diabetes Care, Pediatric Blood and Cancer, and Biology of Blood and Marrow Transplantation. She serves as a regular reviewer for Diabetes Care, Journal of Clinical Endocrinology and Metabolism, Journal of Clinical Investigation, Pediatric Blood and Cancer, and Pediatric Diabetes.

In addition to her research, she is an active clinician and educator. She spends the majority of her time with patients as well as educating pediatric residents and endocrinology fellows to better care for children with endocrine diseases. She is repeatedly named nationally as an “Exceptional Woman in Medicine” and one of America’s Best Doctors.


Key Articles in Peer-Reviewed Journals
Imel E, Glorieux F, Whyte M, Munns C, Ward L, Nilsson O, Simmons J, Padidela R, Namba N, Cheong H, Pitukcheewanont P, Sochett E, Hogler W, Muroya K, Tanaka H, Gottesman G, Biggin A, Perwad F, Mao M, Chen C, Skrinar A, San Martin J, Portale A. Burosumab versus Continuation of Conventional Therapy in Children with X-Linked Hypophosphatemia: A Randomised, Active-Controlled, Open-Label, Phase 3 Trial. Lancet, 393 (10189) June 2019, 2416-2427. PMID 31104833
Lazow M, Jaser S, Cobry E, Garganta M, Simmons J. Stress, Depression, and Quality of Life Among Caregivers of Children with Osteogenesis Imperfecta. Journal of Pediatric Health Care, 33(4) June 2019, 437-445. PMID 30827754
Whyte M, Simmons J,.Moseley S, Fujita K, Bishop N, Salman N, Taylor J, Phillips D, McGinn M, cAlister W. Hypophosphatasia: Seven-Year Outcomes or Life-Threatening Disease in Infants and Young Children Treated with Asfotase Alfa. Lancet Diabetes Endocrinology, 7(2), February 2019, 93-105. PMID 30558909
Colazo J, hlu J, Dahir K, Simmons J. Neurological Symptoms in Hypophosphatasia. Osteoporosis International, 30 (2) February 2019, 469-480. PMID 30215116
Bergner E, Williams R, Hamburger E, Lyttle M, Davis A, Malow B, Simmons J, Lybarger C, Capin R, Jaser S. Sleep in Teens with Type 1 Diabetes: Perspectives From Adolescents and Their Caregivers. Diabetes Educ, 44(6), December 2018, 541-548. PMID 30193548
Garganta M, Jaser S, Lazow M, Schoenecker J, Cobry E, Hays S, Simmons J. Cyclic Bisphosphonate Therapy Reduces Pain and Improves Physical Functioning in Children with Osteogenesis Imperfecta. BMC Musculoskeletal Disorders, 19(1) September 2018, 344. PMID 30249227
Chemaitilly W, Cohen L, Mostoufi-Moab S, Patterson B, Simmons J, Meacham L, van Santen H, Sklar C. Endocrine Late Effects In Childhood Cancer Survivors. Journal of Clinical Oncology, 36 (21) July 2018, 2153-215B. PMID 29874130
Simmons JH, Foster NC, Riddlesworth TD, DuBose SN, Redondo MJ, Liu E, Freemar M. Sex and age-dependent effects of celiac disease on growth and weight gain in children with type diabetes: Analysi of the T1D Exchange clinic registry. Pediatr Diabetes. 19(4) June 2018, 741-748. PMID: 29271067
Dahir K, Tilden D, Warner J, Bastarache L, Smith D, Gifford A, Ramirez A, Simmons J, Black M, Newman J, Denny J. Rare Variants in the Gene ALPL That Cause Hypophosphatasia Are Strongly Associated with Ovarian and Uterine Disorders. Journal of Clinical Endocrinology and Metabolism, 103(6) June 2018, 2234-2243. PMID 29659871
Chew J, Soslow J, Thurm C, Hall M, Dodd D, Feingolo B, Simmons J, Godown J. Heart Transplantation in Children with Turner Syndrome: Analysis of a Linked Dataset. Pediatric Cardiology, 39(3) March 2018, 610-616. PMID 29299618
Datye KA, Boyle CT, Simmons JH, Moore DJ, Jaser SS, Sheanon N, Kittelsrud JM, Woemer SE, Miller KM. Timing of meal insulin and its relation to adherence to therapy in type I diabetes. J Diabetes Sci Technol.12(2) March 2018, 349-355. PMID: 28895431
Craig M, Prinz N, Boyle C, Campbell F, Jones T, Hofer S, Simmons J, Holman N, Tham E, Fröhlich-Reiterer E, Dubose S, Thornton H, King B, Maahs D, Holl R, Warner J, on behalf of the Australasian Diabetes Data Network (ADDN), the T1D Exchange Clinic Network (T1DX), the National Paediatric Diabetes Audit (NPDA) and the Royal College of Paediatrics and Child Health, and the Prospective Diabetes Follow-up Registry (DPV) initiative. Prevalence of Celiac Disease in 52,721 Youth with Type 1 Diabetes: international comparison across three continents. Diabetes Care. 40 (8) August 2017, 1034-1040. PMID: 28546222
Clement S, Kremer L, Verburg F, Simmons J, Goldfarb M, Peeters R, Alexander E, Bardi E, Brignardello E, Constantine L, Dinauer C, Drozd V, Felicetti F, Frey E, Heinzel A, Van den Heuvel-Eibrink M, Huang S, Links T, Lorenz K, Mulder R, Neggers S, Nieveen van Dijkum E, Oeffinger K, van Rijn R, Rivkees S, Ronckers C, Schneider A, Skinner R, Wasserman J, Wynn T, Hudson M, Nathan P, Van Santen H. Balancing the Benefits and Harms of Thyroid Cancer Surveillance in Survivors of Childhood, Adolescent, and Young Adult cancer: Recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group in Collaboation with the PanCareSurFup Consortium. Cancer Treat Rev.63, Novembe 2017, 28-39. PMID: 29202445
Jaser S, Foster N, Nelson B, Kittelsrud J, DiMeglio L, Quinn M, Willi S, Simmons J. Sleep in children with type 1 diabetes and their parents the T1D Exchange. Sleep Medicine. 39 December 2017, 108-115.
Jaser S, Lord J, Simmons J. Malow B. Brief report: Sleep Disturbances in Young Children with Type 1 Diabetes. Diabetes Res Clin Pract. 120 August 2016, 232-234. PMID: 27599087
Libman I, Miller K, DiMeglio L, Bethin K, Katz M, Shah A, Simmons J, Haller M, Raman S, Tamborlane WV, Coffey JK, Saenz AM, Beck RW, Nadeau KJ; T1D Exchange Clinic Network Metformin RCT Study Group. Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes: A Randomized Clinical Trial. JAMA. December 2015 314(21), December 2015, 2241-50.
S, Tamberlane W, Coffey J, Saenz A, Beck R, Nadeau K. Effect of metformin added to insulin on glycemic control among overweight/obese adolescents with type 1 diabetes mellitus: a randomized clinical trial.  JAMA. 314 (21) November 2015, 2241-50. PMID: 26624824
Lindell R, Koh S, Alvarez J, Koyama T, Esbenshade E, Simmons J, Friedman D. Knowledge of diagnosis, treatment history, and risk of late effects among childhood cancer survivors and parents: the impact of a survivorship clinic. Pediatric Blood and Cancer. 62(8) August 2015, 1444-51. PMID: 25894324
Fleming G, Simmons J, Xu M, Gesell S, Brown R, Cutrer W, Gigante J, Cooper W. A Facilitated Peer Mentoring Program for Junior Faculty Improves Professional Development and Peer Networking. Academic Medicine. 90 (6) June 2015, 819-26.  PMID: 25830537
Willi S, Miller K, DiMeglio L, Klingensmith G, Simmons J, Tamborlane W, Nadeau K, Kittelsrud J, Huckfeldt P, Beck R , Lipman T for the T1D Exchange Clinic Network. Racial and Ethnic Disparities in Management and Clinical Outcomes among Children with Type 1 Diabetes. 135(3) March 2015, 424-34. PMID: 25687140
Blackman S, Raghinaru D, Adi S, Simmons J, Ebner-Lyon L, Chase P, Tamborlane W, Schatz D, Block J, Litton J, Raman V, Foster N, Kollman C, DuBose S, Miller K, Beck R. Insulin pump use in young children in the T1D Exchange Clinic Registry is associated with lower hemoglobin A1c levels than injection therapy. Pediatric Diabetes. 15 (8), December 2014, 564-572 PMID: 24494980
Sheedy C, Xu M, Saville B, Simmons J. Vitamin D Abnormalities: More Common in U.S. Children with T1D Than in Healthy Children. Journal of Diabetes Mellitus. 4, October 2014, 324-333.
Esbenshade A, Sopfe J, Zhao Z, Li Z, Campbell C, Simmons J, Friedman D. Screening for Vitamin D Insufficiency in Pediatric Cancer Survivors. Pediatric Blood and Cancer. 61 (4), April 2014, 723-8. PMID: 24194420
Simmons J, Sheedy C, Lee H, Koh S, Alvarez, J, Koyama T, Friedman D. Prevalence of 25-Hydroxyvitamin D Deficiency in Child and Adolescent Patients Undergoing Hematopoietic Cell Transplantation Compared to a Healthy Population. Pediatric Blood and Cancer. 60 (12), December 2013, 2025-30. PMID: 23868793
Simmons J, Chen V, Miller K, McGill J, Bergenstal R, Goland R, Harlan D, Largay J, Massaro E, Beck R. Differences in the Management of Type 1 Diabetes among Adults under Excellent Control Compared with Those under Poor Control in the T1D Exchange Clinic Registry. Diabetes Care. 36 (11), November 2013, 3573-77. PMID: 24026543 PMCID: PMC3816911
Esbenshade E, Simmons J, Koyama T, Lindell R, Friedman D. Obesity and Insulin Resistance in Pediatric Acute Lymphoblastic Leukemia Worsens During Maintenance Therapy. Pediatric Blood and Cancer. 60(8), August 2013, 1287-91. PMID: 23444342
Miller K, Beck R, Bergenstal R, Goland R, Haller M, McGill J, Rodriguez H, Simmons J, Hirsch I for the T1D Exchange Clinic Network. Evidence of a Strong Association between Frequency of Self-Monitoring of Blood Glucose and Hemoglobin A1c Levels in T1D Exchange Clinic Registry Participants. Diabetes Care. 36(7), July 2013, 2009-2014. PMID: 23378621 PMCID: PMC3687326
Elfers C, Simmons J, Roth C. Glucagon-Like-Peptide-1 Agonist Exendin-4 Leads to Reduction of Weight and Caloric Intake in a Rat Model of Hypothalamic Obesity.  Hormone Research in Paediatrics. 78(1), July 2012, 47-53.  PMID: 22831885
Simmons J, Shoemaker A, Roth C. Treatment with Glucagon-Like-Peptide-1 Agonist Exendin-4 in a Patient with Hypothalamic Obesity Secondary to Intracranial Tumor. Hormone Research in Paediatrics.  78 (1), July 2012, 54-58.  PMID: 22831918
Whyte M, Greenberg C, Salman N, Bober M, McAlister W, Wenkert D, VanSickle B, Simmons J, Edgar T, Bauer M, Hamdan M, Bishop N, Lutz, R, McGinn M, Craig S, Moore J, Taylor J, Cleveland R, Cranley W, Lim R, Thacher T, Mayhew J, Downs M, Millan J, Skrinar A, Crine P, Landy H. Enzyme Replacement Therapy In Life-Threatening Hypophosphatasia. New England Journal of Medicine. 366 (10), March 2012, 904-913. PMID: 22397652
Simmons J, Raines M, Ness K, Hall R, Gebretsadik T, Mohan S, Spagnoli A. Metabolic Control and Bone Health in Adolescents with Type 1 Diabetes.   International Journal of Pediatric Endocrinology. 2011(13), November 2011. PMID: 22029838 PMCID: PMC3215174
Simmons J, Chow E, Koehler E, Esbenshade A, Sanders J, Smith LA, Friedman D. Significant 25-hydroxyvitamin D deficiency in child and adolescent survivors of Acute Lymphoblastic Leukemia: Treatment with chemotherapy compared with allogeneic stem cell transplant. Pediatric Blood and Cancer. 56(7), July 2011, 1114-1119. PMID: 21488156 PMCID: PMC3135735
Esbenshade E, Simmons J, Koyama T, Koehler E, Whitlock J, Friedman, D. Body Mass Index and Blood Pressure Changes over the Course of Treatment of Pediatric Acute Lymphoblastic Leukemia. Pediatric Blood and Cancer. 56:3, March 2011, 372-378. PMID: 20860019 PMCID: PMC3713225
Simmons J, Klingensmith G, McFann K, Rewers M, Emery L, Taki I, Liu E, Hoffenberg E. Celiac Autoimmunity in Children with Type 1 Diabetes: A two-year follow-up. J Pediatr. 158:2, February 2011, 276-281.e1. PMID: 20817171 PMCID: PMC2999645
Chow E, Simmons J, Roth C, Baker KS, Hoffmeister P, Sander J, Friedman D. Increased cardiometabolic traits in pediatric survivors of acute lymphoblastic leukemia treated with hematopoietic cell transplantation. Biology of Blood and Marrow Transplatation. 16:12, December 2010, 1674-1681. PMID: 20685399 PMCID: PMC2975816
Van Sickle B, Simmons J, Hall R, Raines M, Ness K, Spagnoli A. Increased circulating IL-8 is associated with reduced IGF-1 and related to poor metabolic control in adolescents with type 1 diabetes mellitus. Cytokine. 48:3, December 2009, 290-294. PMID: 19773182 PMCID: PMC2767424
Simmons J, Klingensmith G, McFann K, Rewers M, Taylor J, Emery L, Taki I, Vanyi S, Liu E, Hoffenberg E. Impact of Celiac Autoimmunity on Children with Type 1 DiabetesJ Pediatr. 150(5), May 2007;, 461-6
Simmons J, McFann K, Brown A, Rewers A, Follansbee D, Temple-Trujillo R, Klingensmith G. Reliability of the Diabetes Fear of Injecting and Self-Testing Questionnaire (D-FISQ) in Pediatric Patients with Type 1 Diabetes.  Diabetes Care. 30:4, April 2007, 987-988. PMID: 17392558
Simmons J, Zeitler P, Fenton L, Abzug M, Fiallo-Scharer R, Klingensmith G. Rhinocerebral mucormycosis complicated by internal carotid artery thrombosis in a pediatric patient with type I diabetes mellitus:  a case report and review of the literature. Pediatric Diabetes. 6:4, December 2005, 234-238. PMID: 16390393
Peer-reviewed Educational Curriculae
Cutrer W, Brown R, Fleming G, Simmons J, Cooper W, Gigante J. Junior Faculty Development Program Using Facilitated Peer Mentoring.  MedEdPORTAL; 2014. Available from: mededportal.org/publication/9905.
Case Series and Case Reports:
Sopfe J, Simmons J. Failure to Thrive, Hyponatremia, and Hyperkalemia in a Neonate. Pediatric Annals. 42:5, May 2013, 74-79.
Simmons J, Miller E, Travers T. Hyponatremia in a Neonate: A Case Report.  Current Opinion in Pediatrics. 17, August 2005, 525-527.
Maniatis A, Simmons J, Zeitler P. Hypothalamic Obesity in a Patient with Craniopharyngioma: Dysregulation of Neurohormonal Control of Energy Balance.  Current Opinion in Pediatrics. 17:2, April 2005, 275-279
Invited Review Articles
Simmons J. Best Practices In: Recognizing and Diagnosis Hypophosphatasia. Clinical Endocrinology News. 8(11), November 2013.
Gregory J, Moore D, Simmons J.  Type I Diabetes:  A Review.  Pediatrics in Review. 34: 5, May 2013, 203-215.
Frangoul H, Najjar J, Simmons J, and Domm J. Long term follow-up and management guidelines in pediatric patients after all-HSCT.  Seminars in Hematology. 49:1, January 2012, 94-103.
Moore D, Gregory J, Kumah-Crystal Y, and Simmons J. Mitigating Micro- and Macro-Vascular Complications of Diabetes Beginning in Adolescence.  Vascular Health and Risk Management. 5, November 2009, 1015-1031.
Simmons J, Zeitler P, and Steelman J. Advances in the Diagnosis and Treatment of Pediatric Osteoporosis.  Advances in Pediatrics. 54, 2007: 85-114.
Simmons J, Zeitler P. Osteopenia in Pediatric Patients: When and How to Intervene.  Curr Opin Endocrinol Diabetes. 13, January 2006, 21-25.
Rewers M, Liu E, Simmons J, Redondo M, Hoffenberg E.  Celiac disease associated with type 1 diabetes mellitus.  Endocrinol Metab Clin N Am.  33:1, March 2004, 197-214.
Invited Editorials
Simmons J. Growth abnormalities in pediatric ALL survivors exposed to lower-dose cranial radiation therapy: The need for continued surveillance.  Pediatric Blood and Cancer. 56:2, Feb 2011, 173-174. PMID: 21140478
Esbenshade A, Simmons J, Friedman D. BMI Alterations During Treatment of Childhood ALL- A Response. Pediatric Blood and Cancer. 58:6, June 2012, 1000.
Abstracts and Posters
Imel E, Whyte M, Munns C, Portale A, Ward L, Nilsson 0, Simmons J, Padidela R, Namba N, Cheong H, Hogler W, Mao M, Chen C, Skrinar, San Martin J, Glorieux. Burosumab Resulted in Better Clinical Outcomes than Continuation with Conventional Therapy in Younger and Older Children with X-Linked Hypophosphatemia. Rapid Oral Presentation at the American Society for Bone and Mineral Research (ASBMR) (Orlando, FL September 2019).
Hogler W, Imel E, Whyte M, Munns C, Portale A, Ward L, Nilsson 0, Simmons J, Padidela R, Namba N, Cheong H, Mao M, Chin C, Skrinar A, San Martin J, Glorieux F. Burosumab Resulted in Better Clinical Outcomes than Continuation with Conventional Therapy in Both Younger (1-4 years old) and Older (5-12 years old) Children with X-Linked Hypophosphatemia. Oral presentation at the European Society of Pediatric Endocrinology (ESPE) (Vienna, Austria September 2019).
Simmons J, Rush E, Petryk A, Zhou S, Martos-Moreno G. Dual X-ray Absorptiometry in Children with Hypophosphatasia Treated with Asfotase Alfa: A Pooled Post Hoc Analysis. European Society for Pediatric Endocrinology Annual Meeting (Vienna, Austria September 2019).
Quinn M, Bailey R, Foster N, Simmons J, Eyth E, Rodriguez M, Corathers S, Levey C, Sheanon N, Wasserman R, Seiple D, Sparling D, Adkins D, O'Neill A. DeSalvo D. Diabetes Management Supplies in Youth ith Type 1 Diabetes: Don't Leave Home Without Them! American Diabetes Association National Meeting. (San Francisco, CA June 2019).
Sherr J, Foster N, Bethin K, Fox L, Mastrandrea L, Nathan B, Redondo M, Silverstein J, Simmons J, Clements M, Tamborlane W, Thraikill K, Wong J, Wood J. HbAlc Trajectories from Time of Diagnosis in Youth with Type 1 Diabetes. American Diabetes Association National Meeting. (San Francisco, CA June 2019)
Ward L, Imel E, Whyte Munns C, Portale A, Hogler W, Simmons J, Padidela R, Nilsson O, Namba N, Cheong H, Mao M, Chen C, Skrinar A, San Martin J, Glorieux F. Burosumab Resulted in Greater Improvement in Rickets than Conventional Therapy in Younger (1-4 years old) and Older (5-12 years-old) Children with X-linked Hypophosphatemia (XLH). Oral presentation-at the International Conference on Children's Bone Health (ICCBH) (Salzburg, Austria, June 2019).
Simmons J, mel E, Glorieux F, Munns C, Portale A, Ward L, Nilsson O, Padidela R, Namba N, Cheong H, Mao M, Chen C, Skrinar A, San Martin J, Whyte M. Burosumab Showed Greater Improvement in Rickets, Phosphate Metabolism, Growth, and Mobility than Conventional Therapy in Children with X-Linked Hypophosphatemia. Oral presentation at the Pediatric Academic Societies National Meeting (Baltimore MD, April 2019)
Tilden D, Sheehan J, Newman J, Meiler J, Capra T, Simmons J, Black M, Dahir K. The Clinical Utility of Gene Seguencing in Mypophosphatasia: I:essons from Patients with Two Rare Variants. Presidential Poster Award Winner, Endocrine Society National Meeting (New Orleans LA, March 2019)
Imel E, Whyte M, Munns C, Portale A, Ward L, Nilsson O, Simmons J, Padidela R, Namba + N, ~heong H, Mao M, Chen C, Skrinar A, San Martin J, Glorieux F. Burosumab Resulted in Greater Improvement in Rickets than Conventional Therapy in Children with XJ inked Hypophosphatemia (XLH). Oral presentation at the Endocrine Society National Meeting (New Orleans, LA, March 2019
Hamburger E, Munjal H Lyttle M, Williams R, Simmons J, Malow B, Jaser S. The Impact of Randomized Pilot Sleep Promotion Program for Adolescents with Typ~ 1 Diabetes. Oral presentation at the Society for Behavioral Medicine Annual Meeting (Washington DC, March 2019).
Imel E, Whyte M, Munns C, Portale A, Ward L, Nilsson O, Simmons J, Padidela R, Namba JL N, Cheong H, Mao M, Chen C, Skrinar A, San Martin J, Glorieux F. Burosumab Improved Rickets, Phosphate Metabolism, and Clinical Outcomes Compared to Conventional Therapy in Children with XLH. Oral presentation at the American Society for Mineral and Bone Research (Montreal, QC, Canada, October 2018).
Nilsson O, Whyte M, Imel E, Munns C, Portale A, Ward L, Simmons J, Padidela R, Namba N, Cheong H, Mao M, Skrinar A, Chen C, San Martin J, Glorieux F. Burosumab Improved Rickets, Phosphate Metabolism, and Clinical Outcomes Compared to Conventional Therapy in Children with X-Linked Hypophosphatemia (XLH)-A Randomized Controlled Phase 3 Study. Oral presentation at the European Society for Pediatric Endocrinology (Athens, Greece September 2018)
Hu R, Colazo J, Dahir.K, Simmons J. Neurological Findings in Hypophosphatasia Patients. Presented at The Endocrine Society National Meeting (Chicago March 2018)
Tilden D, Simmons J, Black M, Smith D, Newman J, Bastarache L, Warner J, Dahir K. Nine Rare Variants in the Tissue-Nonspecific Alkaline Phosphatase (ITNSALP) Gene: Refining the Phenotype of Hypophosphatasia. Presented at The Endocrine Society National Meeting (Chicago March 2018)
Tilden D, Simmons J, Black M, Smith D, Newman J, Bastarache L, Warner J, Dahir K. Rare Variants in the ALPL Gene are Highly Associated with Ovarian and Uterine Disorders. Presented at The Endocrine Society National Meeting (Chicago March 2018), Presidential Poster Award Winner
Whyte M, Simmons J, Moseley S, Bishop N. Infants and Young children with LifeJct- Threatening Hypophosphatasia Treated with Asfotase Alfa: Final 7-Year Radiographic, Growth, and Functional Outcomes. Presented as an oral presentation at The Endocrine Society National Meeting (Chicago March 2018)
Jaser J, Foster N, Nelson B, Kittelsrud J, Humphrey L, DiMeglio L, Quinn M, Willi S, Simmons J. Does Sleep Matter? Associations Between Child Sleep, Glycemic Control, and Parental Well-Being in the T1D Exchange Clinic Registry. Oral Presentation at the International Society for Pediatric and Adolescent Diabetes (Valencia, Spain Oct 2016).
Nadeau K, Miller K, Nathan B, Bacha F, Katz M, Simmons J, Gottschalk M, Tsalikian E, Tansey M, Copeland K, DiMeglio L, Cree-Green M, Libman I, Haller M. Effect of Metformin on Endothelial Function in Overweight Adolescents with Type 1 Diabetes” Oral Presentation at the International Society for Pediatric and Adolescent Diabetes (Valencia, Spain Oct 2016).
Chew J, Soslow J, Thurm C, Hall M, Dodd D, Feingold B, Simmons J, Godown J. Heart Transplantation in Children with Turner Syndrome: Analysis of a Linked Dataset. Presented at the American Heart Association Annual Meeting (Anaheim Ca, November 2017).
Whyte M, Simmons J, Moseley S, Bishop N. Infants and Young children with Life-Threatening Hypophosphatasia Treated with Asfotase Alfa: Final 7-Year Radiographic, Growth, and Functional Outcomes. Accepted for Oral Presentation at The Endocrine Society National Meeting (Chicago March 2018)
Tilden D, Simmons J, Black M, Smith D, Newman J, Bastarache L, Warner J, Dahir K. Rare Variants in the ALPL Gene are Highly Associated with Ovarian and Uterine Disorders. Accepted for Presentation at The Endocrine Society National Meeting (Chicago March 2018)
Tilden D, Simmons J, Black M, Smith D, Newman J, Bastarache L, Warner J, Dahir K. Nine Rare Variants in the Tissue-Nonspecific Alkaline Phosphatase (TNSALP) Gene: Refining the Phenotype of Hypophosphatasia. Accepted for Presentation at The Endocrine Society National Meeting (Chicago March 2018)
Simmons J, Bishop N, Lutz R, Zhang H, Fujita K, Whyte M. Skeletal, Growth, and Functional Improvements in Infants and Young Children with Life-Threatening Hypophosphatasia Treated with Asfotase Alfa for 5 years.  Accepted for presentation at the American Society for Bone and Mineral Research (Atlanta September 2016)
Jaser J, Foster N, Nelson B, Kittelsrud J, Humphrey L, DiMeglio L, Quinn M, Willi S, Simmons J. Sleep quality associated with glycemic control in adolescents in the T1D Exchange Clinic Registry.  Presented at American Diabetes Association’s Annual Scientific Sessions (New Orleans June 2016).
Simmons J, Riddlesworth T, Foster N, Liu E, Freemark M. The effect of celiac disease on growth in children and adolescents with type 1 diabetes. Presented at American Diabetes Association’s Annual Scientific Sessions (New Orleans June 2016)
Clement S, Kremer L, Ferberg F, Simmons J, Goldfarb M, Peeters R, Alexander E, Bardi E, Brignardello E. Constine L, Dinauer C, Drozd V, Felicetti F, Frey E, Heinzel A, Van del Heuve-Eibrink M, Huang S, Links T, Lorenz K, Mulder R, Neggers S, Nieveen van Dijkum E, Oeffinger K, Rijn R, Rivkees S, Ronckers C, Schneider A, Skinner R, Wasserman J, Wynn T, Hudson M, Nathan P, Van Santen H. Recommendations for Thyroid Cancer Surveillance among Survivors of Childhood Cancer: a Report from the International Late Effects of Childhood Cancer Guideline Harmonization Group.  Presented at the Endocrine Society National Meeting (Boston, MA April 2016).
Garganta M, Jaser S, Lazow M, Hays S, and Simmons J. Cyclic Bisphosphonate Therapy Reduces Bone Pain in Children with Osteogenesis Imperfecta. Presented at the The Endocrine Society National Meeting (Boston, MA April 2016)
Simmons J, Bishop N, Lutz R, Zhang H, Fujita K, Whyte M. Hypophosphatasia:  functional, skeletal and growth Improvements in Infants and Young Children Treated with Asfotase Alfa for 5 Years.  Presented at the American College of Genetics and Metabolism National Meeting (Tampa, FL March 2016)
Datye KA, Boyle CT, Simmons JH, Moore D, Jaser S, Sheanon N, Kittelsrud J, Woerner S, Miller K, Beck R. Timing of meal insulin delivery and its relation to missed insulin doses. Oral Presentation at the Diabetes Technology Society National Meeting (Baltimore October 2015).
Clement S, Kremer L, Ferberg F, Simmons J, Goldfarb M, Peeters R, Alexander E, Bardi E, Brignardello E. Constine L, Dinauer C, Drozd V, Felicetti F, Frey E, Heinzel A, Van del Heuve-Eibrink M, Huang S, Links T, Lorenz K, Mulder R, Neggers S, Nieveen van Dijkum E, Oeffinger K, Rijn R, Rivkees S, Ronckers C, Schneider A, Skinner R, Wasserman J, Wynn T, Hudson M, Nathan P, Van Santen H. Recommendations for Thyroid Cancer Surveillance among Survivors of Childhood Cancer: a Report from the International Late Effects of Childhood Cancer Guideline Harmonization Group.  Oral Presentation at the European Society for Pediatric Endocrinology (Barcelona, Spain September  2015)
Nadeau K, Miller K, DiMeglio L, Bethin K, Katz M, Shah A, Simmons J, Haller M, Raman S, Tamborlane W, Coffee J, Saenz A, Beck R, Libman I for the T1D Exchange Clinic Network Metformin RCT Study Group, Effect of Metformin on Cardiovascular Risk Factors in Overweight Adolescents with Type 1 Diabetes.  Oral Presentation at the American Diabetes Association’s Annual Scientific Sessions (Boston June 2015).
Nadeau K, Miller K, DiMeglio L, Bethin K, Katz M, Shah A, Simmons J, Haller M, Raman S, Tamborlane W, Coffee J, Saenz A, Beck R, Libman I for the T1D Exchange Clinic Network Metformin RCT Study Group, Effect of Metformin on Cardiovascular Risk Factors in Overweight Adolescents with Type 1 Diabetes.  Oral presentation at the Endocrine Society’s National Meeting (San Diego March 2015).
Dhaliwal R, Foster N, DiMeglio L, Manseau K, Shah V, Kittelsrud J, Simmons J, Mastrandrea L, Styner M, Beck R, Weinstock R. Osteopenia and Osteoporosis in Adult Females with Type 1 Diabetes: Results from the T1D Exchange Registry. Presented at the American Society for Bone and Mineral Research (ASBMR) (Houston, Tx, 9/ 2014)
Whyte M, Bishop N, Simmons J, Lutz R, Vallée M, Melian A, Odrljin T. Asfotase alfa: Sustained efficacy and tolerability in infants and young children with life‐threatening hypophosphatasia. Presented at the Bone Research Society International Meeting (Sheffield, UK 6/ 2014).
Fleming G, Simmons J, Brown R, Cutrer W, Gigante J, Cooper W. Impact of a Department-Wide Facilitated Peer Mentoring Program for Junior Faculty. Presented at the Pediatric Academic Societies National Meeting (Vancouver 5/ 14).
Simmons J, DuBose S, Miller K, DiMeglio L, Beck R, and Freemark M. Celiac Disease and Type I Diabetes: growth, weight gain, and family concordance in the T1D Exchange. Presented at the Pediatric Academic Societies National Meeting (Vancouver 5/ 14).
Whyte M, Simmons J, Lutz R, Vallée M, Melian A, Odrljin T, Bishop N. Asfotase alfa: Sustained efficacy and tolerability in infants and young children with life‐threatening hypophosphatasia. Presented at the European Calcified Tissue Society International Meeting (Prague, CK 5/ 2014)
Whyte M, Bishop N, Simmons J, Lutz R, Vallée M, Melian A, Odrljin T. Asfotase alfa: Sustained efficacy and tolerability in infants and young children with life‐threatening hypophosphatasia. Presented at the Pediatric Academic Societies National Meeting (Vancouver 5/ 14).
Fleming G, Simmons J, Brown R, Cutrer W, Gigante J, Cooper W. A Junior Faculty Development Program: A Snapshot of Pre-Participation Knowledge, Skills, and Attitudes. Presented at the Pediatric Educational Excellence Across the Continuum (PEEAC) Conference (Arlington, VA 10/ 13)
Miller K, Beck R, Laffel L, Largay J, Shanmughan S, Rodriguez H, Manseau K, Klingensmith G, Simmons J, Tamborlane W. The Attention Deficit Hyperactivity Disorder (ADHD) impacts diabetes management and glycemic control among adolescents and young adults with type 1 diabetes. Presented at the American Diabetes Association Annual Scientific Sessions. (Chicago, IL 6/13).
Bondi S, Simmons J, Lowen D. The Effect of Social Services Reporting on Diabetes Control in Children. Presented at the Pediatric Academic Societies National Meeting. (Washington DC 4/13).
Simmons, J, Greenberg C, Salman N, Bober M, McAlister W, Wenkert D, VanSickle B, Edgar T, Bauer M, Hamdan M, Bishop N, Lutz, R, McGinn M, Craig S, Moore J, Taylor J, Cleveland R, Cranley W, Lim R, Thacher T, Mayhew J, Downs M, Millan J, Skrinar A, Crine P, Landy H, Whyte M.  Improvement in Rickets and Pulmonary Function in Infants with Life-Threatening Hypophosphatasia (HPP) during Bone-Targeted Enzyme Replacement Therapy.  Presented at the Pediatric Academic Societies National Meeting. (Boston, MA 4/12)
Simmons J, Lee H, Sheedy C, Friedman D. Vitamin D Status, Sun Exposure, and Dietary Intake of Vitamin D in Pediatric Hematopoietic Cell Transplant Patients at Transplant. Presented at the Pediatric Academic Societies National Meeting. (Boston, MA 4/12).
Simmons J, Chow E, Koehler E, Esbenshade A, Smith LA, Friedman D. Significant 25-hydroxyvitamin D deficiency in pediatric ALL survivors: treatment with conventional chemotherapy compared with allogeneic hematopoietic stem cell transplant.  Presented at the 11th International Conference on Long-Term Complications of Treatment of Children and Adolescents for Cancer, sponsored by the National Cancer Institute and St. Jude Children’s Research Hospital. (Williamsburg, VA 6/10)
Chow E, Simmons J, Roth C, Baker KS, Hoffmeister P, Sander J, Friedman D. Increased cardiometabolic traits in pediatric survivors of acute lymphoblastic leukemia treated with hematopoietic cell transplantation. Presented at the 11th International Conference on Long-Term Complications of Treatment of Children and Adolescents for Cancer, sponsored by the National Cancer Institute and St. Jude Children’s Research Hospital. (Williamsburg, VA 6/10)
Esbenshade E, Simmons J, Koyama T, Koehler E, Whitlock J, Friedman, D. Body Mass Index and Blood Pressure Changes over the Course of Treatment of Pediatric Acute Lymphoblastic Leukemia.  Presented at the 11th International Conference on Long-Term Complications of Treatment of Children and Adolescents for Cancer, sponsored by the National Cancer Institute and St. Jude Children’s Research Hospital. (Williamsburg, VA 6/10)
Van Sickle BJ, Simmons J, Hall R, Raines M, Ness KD, Spagnoli A. Poor Glucose Control in Adolescents with Type 1 Diabetes Mellitus is Associated with Increased Circulating IL-8 but Reduced IGF-1. J Clin Endocrinol Metab, 2008, P2-644. Presented at The Endocrine Society’s 90th Annual Meeting (San Francisco, CA 6/08)
Raines MD, Spagnoli A, Ness KD, Hall R, Simmons J. Decreased IGF-I Levels Are Associated with Low Bone Mineral Density and Poor Glycemic Control in Adolescents with Type I Diabetes Mellitus. J Clin Endocrinol Metab, 2008, P1-274. Presented at The Endocrine Society’s 90th Annual Meeting (San Francisco, CA 6/08)
Hoffenberg E, Simmons J, Klingensmith GJ, et al. Impact of Celiac Autoimmunity in Diabetic Children:  12 month follow-up.  J Pediatr Gastroenterol Nutr, 2007,45,E49. Presented at the  NASPGHAN 19th Annual Meeting (Salt Lake City, UT 10/07)
Hoffenberg E, Simmons J, Klingensmith G, McFann K, Emery L, Rewers M, Taki I, Vanyi S, Liu E. Screening-identified evidence of celiac disease-1year outcome. J Pediatr Gastroenterol Nutr, 2006,43,E43. Presented at the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Annual Meeting. (Orlando, FL. 10/06)
Simmons J, McFann K, Brown A, Rewers A, Cruz E, Klingensmith G. Achieving Pediatric ADA HbA1c Goals:  Insulin Pump Therapy Vs Injection Therapy. Diabetes  2006; 55(1): A413. Presented at the American Diabetes Association Annual Scientific Sessions. (Washington, DC 6/06)
Simmons J, Klingensmith G, McFann K, Rewers M, Zarzycki K, Taki I, Liu E, Hoffenberg E. Impact of Celiac Autoimmunity on Growth, Diabetes Control, and Bone Density of Subjects with Type I Diabetes. Diabetes 2005;54(1): A456. Presented at the American Diabetes Association Annual Scientific Sessions (San Diego, CA 6/05)
Simmons J, Klingensmith G, Emery L, McFann K, Rewers M, Zarzycki K, Taki I, Liu E, Hoffenberg E. Impact of Celiac Autoimmunity on Growth, Diabetes Control, and Bone Density of Subjects with Type I Diabetes.  Presented at the Juvenile Diabetes Research Foundation Fellows’ Conference (Chantilly, VA 3/05)
Simmons J, Emery L, Klingensmith G, Zarzycki K, Taki I, Liu E, Rewers M, Hoffenberg E. Impact of Celiac Autoimmunity on Subjects with Type 1 Diabetes. Journal of Investigative Medicine. 2005;53(1):S147.  Presented at the Western Society for Pediatric Research Meeting (Carmel, CA 2/05)
Rewers M, Klingensmith G, Redondo M, Simmons J, Norris J, Eisenbarth G, Hoffenberg E. Celiac Disease in Type 1 Diabetes: Screening and Follow-up.  2004;53(supp2):A1780.  Presented at the American Diabetes Association Annual Scientific Sessions (Orlando, FL 6/04)
Steelman J, Zeitler P, Simmons J, Schissel D, Giller R, Frangoul H. Evaluation for Osteoporosis in Pediatric Bone Marrow Transplant Patients. Pediatric Research. 2003;53 (supp4):A858. Presented at the Pediatric Academic Society Annual Meeting (5/03)
National Invited Presentations
July 2016 -- “Hypophosphatasia: An Update” Soft Bones National Meeting, Nashville, TN
March 2015 -- “Clinical Manifestations of HPP: Genetics and Physiology”, Ancillary Symposium, Endocrine Society National Meeting, San Diego, CA
April 2012 -- “Uncommon Metabolic Bone Diseases in Pediatric Patients: Opportunities for Improving Diagnosis and Treatment” Satellite Symposium, Pediatric Academic Society National Meeting, Boston MA
March 2016 “Timing of Meal Insulin Delivery and its Relation to Missed Insulin Doses” Type I Diabetes Exchange National Meeting, Tampa FL.
June 2015 “When Steroids are Sweet: Steroid-Induced Pediatric Diabetes”.  Invited Symposium presentation at the American Diabetes Association 75th Anniversary Scientific Sessions, Boston MA
April 2015 “Habits of Highly Successful Academicians: Making Your Grandmother (and Your Department Chair) Proud.”  Workshop presentation at the Pediatric Academic Societies and Asian Society for Pediatric Research Meeting.  San Diego, CA
March 2015 “The Effect of Celiac Disease on Children and Adolescents with Type 1 Diabetes”.  Type I Diabetes Exchange National Meeting, Tampa FL
September 2014 “Pediatric Endocrinology: A Review” PREP the Course.  Sponsored by the American Academy of Pediatrics, Denver, CO
March 2014 “Celiac Disease and Type I diabetes”  Type I Diabetes Exchange National Meeting, Tampa FL
March 2014 “Pediatric Endocrinology: A Review” PREP the Course.  Sponsored by the American Academy of Pediatrics, Tempe, AZ
March 2012 “Celiac Disease and Type I diabetes”  Type I Diabetes Exchange National Meeting, Tampa FL
March 2012      “Pediatric Endocrinology: A Review” PREP the Course.  Sponsored by the American Academy of Pediatrics, New Orleans, LA
June 2011 “Pediatric Endocrinology: A Review” PREP the Course.  Sponsored by the American Academy of Pediatrics, Costa Mesa, CA
September 2010 “Pediatric Endocrinology: A Review” PREP the Course.  Sponsored by the American Academy of Pediatrics, Pittsburgh, PA
June 2010 “Pediatric Endocrinology: A Review” PREP the Course.  Sponsored by the American Academy of Pediatrics, Anaheim CA
April 2010 “Annual Incidence of Celiac Autoimmunity in patients with Type I   diabetes” Type I Diabetes Exchange National Meeting, Tampa FL
International Invited Presentations
April 2019 -- "Burosumab Showed Greater Improvement in Rickets, Phosphate Metabolism, Growth, and Mobility than Conventional Therapy in Children with X-Linked Hypophosphatemia (XLH). Pediatric Academic Societies National Meeting, Baltimore MD
February 2019 -- " Unusual Presentations of Rickets" PESTO LA Annual Conference, Dallas, Tx
February 2019 -- "A Final Frontier: New T eatments for Pediatric Hypophosphatasia and XLinked Hypophosphatemic•Rickets" PESTOLA Annual Conference, Dallas, Tx
July 2018 -- "Pediatric Hypophosphatasia: Update 2018" MAGIC Foundation Annual Conference, Chicago, IL
June 2018 -- "Improvements in Skeletal Mineralization, Respiratory of Motor Function, and Growth during Seven Years of Trnatment of Perinatal and Infantile 1-lypophosphatasia. Soft Bones Scientific Meeting, Chicago, IL
July 2017 -- “Pediatric Hypophosphatasia: An Update on Diagnosis and Treatment” MAGIC Foundation Annual Conference, Chicago, IL
July 2017 -- Presentation regarding the clinical efficacy of asfotase alfa to the PBAC (Pharmaceutical Benefits Advisory Committee), Canberra, Australia
July 2017 -- “Pediatric Hypophosphatasia: Improvements in Skeletal Mineralization and Motor Function after Treatment with Enzyme Replacement Therapy”, Lady Cilento Children’s Hospital, Brisbane, Queensland, Australia
July 2017 -- “Pediatric Hypophosphatasia: Improvements in Skeletal Mineralization and Motor Function after Treatment with Enzyme Replacement Therapy”, Westmeade Children’s Hospital, Sydney, New South Wales, Australia
November 2016 -- “ Skeletal, Growth, and Functional Improvements in Children with Hypophosphatasia Treated with Asfotase Alfa for 5 Years” Symposia Presentation, Asian Pacific Pediatric Endocrine Society and the Japanese Society for Pediatric Endocrinology International Meeting, Tokyo, Japan
October 2015 -- “The Long-Term Potential for Infants Treated with Asfotase Alpha” Satellite Symposium, European Society for Pediatric Endocrinology International Meeting, Barcelona, Spain
October 2015 “Which Childhood Cancer Survivors are at Risk for Thyroid Cancer:  A Summary of the Evidence”  Symposia presentation, European Society for Pediatric Endocrinology International Meeting, Barcelona, Spain
May 2014 -- “Clinical Presentation and Pathogenesis of Hypophosphatasia: The Role of Alkaline Phosphatase”. Satellite Symposium, Pediatric Academic Societies and Asian Society for Pediatric Research Meeting , Vancouver, BC
May 2014 “Habits of Highly Successful Academicians: Making Your Grandmother (and Your Department Chair) Proud.”  Workshop presentation at the Pediatric Academic Societies and Asian Society for Pediatric Research Meeting.  Vancouver, BC
Invited Chair, National
April 2016 -- “Hypophosphatasia: New Options in the Management of Alkaline Phosphatase Deficiency” Program Chair, Ancillary Symposium, Endocrine Society National Meeting, Boston MA
March 2015 -- “Avoiding Missteps in the Diagnosis and Management of Hypophosphatasia” Program Chair, Ancillary Symposium, Endocrine Society National Meeting, San Diego CA